Establishment and Development of the First Biobank of Inflammatory Bowel Disease, Suspected to Primary Immunodeficiency Diseases in Iran
Background: Inflammatory bowel disease (IBD) might be an immunodeficiency rather than an excessive inflammatory reaction. IBD, suspected to primary immunodeficiency diseases biobank (IBDSPIDB) as a resource for researches can help improve the prevention, diagnosis, and illness treatment and the health promotion throughout the society. Therefore, we launched the biobank of IBDSPID for the first time in Iran.
Assessment of anemia in patients with various types of inflammatory bowel disease under medical therapy
Background: Anemia is a usual systemic complication of inflammatory bowel disease (IBD) and can be presented in combination of iron deficiency anemia (IDA) and anemia of chronic disease (ACD). In the present study, anemia in IBD was assessed.
Quality of life in inflammatory bowel disease patients: A cross‑sectional study
Background:Inflammatory bowel disease (IBD) has a significant impact on health‑related quality of life (HRQOL). This study aims to investigate the variables which can be attributed to HRQOL in IBD patients.
Relationship between articular and nonarticular manifestations in inflammatory bowel Diseases
Background: Musculoskeletal manifestations (MSM) of inflammatory bowel diseases (IBDs) are usually the most frequent extraintestinal manifestations. However, they are not paid enough attention during regular office visits. This cross‑sectional study aimed to draw a clinical picture of MSM and their relationships with other findings in patients with IBD.
Setting up the First Registry for Inflammatory Bowel Disease, Suspected to Primary Immunodeficiency Diseases in Iran
Background:inflammatory bowel disease (IBD) has been considered a hyperinflammatory state due to disturbed interactions between the immune system and the commensal bacterial flora of the gut and suggesting IBD asa primary immunodeficiencies (PID). Therefore a registry launched about IBD, suspected to PID (IBDSPID) for the first time in Iran to raise awareness about this disease, to identify its risk factors, to early diagnosis and treatment.
Vitamin D Deficiency Associated with Disease Activity in Patients with Inflammatory Bowel Diseases
Background:Evidence exists on the association between vitamin D deficiency and inflammatory bowel diseases (IBD). Aims To investigate whether vitamin D level is associated with disease activity and quality of life in IBD patients.
Background:Pulmonary impairment in patients suffering ulcerative colitis (UC) has been suggested by several investigators using standard pulmonary function tests (PFTs). This changes in pulmonary function associated with minimal respiratory symptoms have been documented, especially in patients with active disease. The aim of this prospective study was to determine airway resistance and lung volumes in patients with UC who have no respiratory symptoms in comparisons to a healthy control group.
Irritable Bowel Syndrome–like Symptoms in Patients with Inflammatory Bowel Disease in Clinical Remission Phase are Related to Gut Inflammation
Background:Symptoms consistent with irritable bowel syndrome (IBS) are common among IBD patients in remission phase, and clinicians have difficulties in interpreting such symptoms as an ongoing disease activity or a coexistent IBS. We investigated if the assessment of Fecal Calprotectin (FC) could be helpful in this regard
Serologic celiac disease in patients with inflammatory bowel disease
Background: There is an association of celiac disease (CD) with several gastrointestinal illnesses. We aimed to determine the prevalence of CD in patients with inflammatory bowel disease (IBD) to evaluate the value of the routine serological tests for CD in these patients.
Linguistic Validation of the Inflammatory Bowel Disease Questionnaire-Short Form (IBDQ-9) in Iranian Population
Background:Quality of life is significantly reduced in patients with inflammatory bowel disease (IBD). As there was no specific instrument for assessment of quality of life of Iranian IBD patients, we aimed to linguistically validate the Inflammatory Bowel Disease Questionnaire-Short Form (IBDQ-9) in Iranian IBD patients.
Hypnotherapy as an Adjuvant for the Management of Inflammatory Bowel Disease: A Case Report
Background: Idiopathic inflammatory bowel diseases (IBDs) significantly affect the quality of life of sufferers. Improved quality of life and patient symptom management may be achieved through integrating psychological/behavioral interventions with pharmacologic treatments.
Endoscopic polypectomy resection of blue rubber bleb nevus lesions in small bowel
Background:Blue rubber bleb nevus syndrome (BRBNS) is a rare disorder characterized by cutaneous and gastrointestinal (GI) venous malformations. The treatment of BRBNS is primarily supportive and ablative. Ablative therapy involves endoscopic or surgical treatment of GI venous malformations. We describe a 20-year-old woman who had multiple venous malformations all over the GI tract as well as cutaneous lesions.
Is microscopic colitis a missed diagnosis in diarrhea-predominant Irritable Bowel Syndrome?
Background: There are controversies about the importance of biopsies of normal colon mucosa in the investigation of patients with diarrhea predominant irritable bowel syndrome (IBS). On the other hand, microscopic colitis may be missed based on normal colonoscopy and laboratory examination in this group of patients.
Background: Ramadan fasting may induce changes in gastrointestinal physiology. The effect of this fasting on inflammatory bowel disease (IBD) is not known. We conducted a cohort study in the month of Ramadan in 2006 to assess the effect of Ramadan fasting on IBD.
Prevalence of osteopenia and osteoporosis and related risk factors in patients with inflammatory bowel disease
PI:Ghazale Taheri Colleagues:Seyed Mohammad Hassan Emami, MD Funded by:Poursina Hakim Digestive Disease Research Center, Isfahan University of Medical Sciences
Evaluation of zinc concentration in serum of patients with Crohn's disease in Isfahan and comparison with control group
PI: Zahra Soltani, Medical Student Colleagues: Rahmat allah Rafiei, MD. Abdolmehdi Baghaei, MD
Primary Sclerosing Cholangitis (PSC) Registry and Monitoring (Surveillance): Feasibility and Application (An Action Research)
PI: Tahere Taheri, Medical Student Colleagues: Abdolmehdi Baghaei, MD
Describe the natural history of Primary sclerosing cholangitis (PSC) in Iranian popular To
PI: Zahra Arefyan, Medical Student Colleagues: Abdolmehdi Baghaei, MD
Digestive Diseases Research Center (DDRC) is an affiliated research center to Poursina Hakim Institute, a private organization for health promotion, patient care, research and education in biomedical sciences especially field of gastrointestinal diseases. Research activities have been begun since 2000, just at the same time that Poursina Hakim Institute initiated its life. By improving and developing research activities, it was needed to have an organization for making policy and supervise research activities in the institute. Since September 2008, Poursina Hakim Research Center was established for this reason. It was approved by Iranian ministry of health as DDRC in 2015. Our research team is comprises of expert researchers with varying interests and disciplines to translate the research from Bench to Bedside to benefit human health and engage in the development of health related technologies.