.Antioxidant Effects of Methanol Extract of Dracocephalum kotschyi in Acetic Acid Induced Rat Colitis Model.
Background: There is a worldwide trend towards substitute synthetic antioxidants with natural alternatives to treat inflammatory bowel disease (IBD) such as ulcerative colitis (UC). This study was conducted to evaluate the effects of Dracocephalum kotschyi extract on tissue injury and oxidative stress in an acetic-acid induced colitis model.
.The Association between Celiac Disease and Eosinophilic Esophagitis among Children, in Isfahan, Iran.
Background: The prevalence of eosinophilic esophagitis (EoE) has increased in recent decades. Recent studies have found that the prevalence of EoE in patients with celiac disease (CD) is much higher compared with the general population. In this study, the prevalence of EoE in children with CD was calculated and their clinical symptoms, endoscopic and histopathological findings were compared.
Digestive Diseases Research Center (DDRC) is an affiliated research center to Poursina Hakim Institute, a private organization for health promotion, patient care, research and education in biomedical sciences in the field of gastrointestinal diseases. Research activities have begun since 2000, just at the same time that Poursina Hakim Institute initiated its activity leading to establishment of Poursina Hakim Research Center in 2008. The institute including the research center was finally approved by the Iranian Ministry of Health and Medical Education as DDRC in 2015. Our research team is comprised of researchers in different fields including medicine, pharmacy, microbiology, pathology, statistics, etc. with the goal to translate research from bench- to-bedside benefiting mankind.